The main campaign of Mewgenics is spread across different regions, and most of them remain locked at first. However, you’ll be able to unlock these regions by playing the game.
Unlocking most of the areas is a simple task. You have to unlock the previous one to move on to the next location. However, some, like the Secret Domains, are tricky to discover. The requirements for unlocking those regions tend to be tricky.
How to unlock all Areas and Acts in Mewgenics
Everyone begins playing at The Alley. The Alley is the first location of Mewgenics, and it comes unlocked by default. It’s going to be the very first mission that you complete as part of your adventure.
| Area | How to Unlock |
|---|---|
| The Alley | As the first area of the game, The Alley is unlocked by default. |
| The Sewers | Finish a run in The Alley. |
| The Caves | Finish a run in The Sewers. This is the third location you’ll access. |
| The Junkyard | Complete The Alley’s hard branch, which is tougher than the default option. |
| The Boneyard | Finish a run in The Junkyard. |
| The Throbbing Domain | This is going to be the first secret area that you can unlock. Once you complete Guillotina’s first boss fight, take the Throbbing Gristle to the Wall of Flesh. Then, take the Putrid Leach from Guillotina’s second boss fight to the Throbbing Artery in The Boneyard. Complete the third boss fight, and equip her head to one of your cats. Then, go to the altar in the Throbbing Domain and sacrifice the cat (that has Guillotina’s head equipped). |
| Desert | Finish a run in The Boneyard and in The Caves. |
| The Bunker | Finish a run in The Desert. |
| The Core | Finish a run in The Bunker. |
| The Crater | Finish a run in The Desert. |
| The Moon | Finish a run in The Crater. |
| The Rift | This is the second secret stage in the game. You’ll meet Pyrophina and Zaratan once you’ve cleared runs on The Moon and The Core. Defeat both of them and take the Burning orb from Pyrophina. Feed it to the Man on the Moon by making a cat stand in front of him while holding the item. Next, charge Zaratana’s Shard by killing 20 enemies with the item equipped. Take the shard to the Coven on the Core and insta-kilit with the Shard. Now, both Pyrophina and Zaratana will return to your house. Once their fight is over, you’ll get a collar. If you get Pyrophina’s collar, take it to the obelisk at the end of The Moon. If you get Zaratana’s collar, take it to the Core obelisk. |
| The Lab | Finish a run in The Core and The Moon. |
| Ice Age | Finish a run in The Lab. |
| The Future | Finish a run in The Lab. |
| The Jurassic | Finish a run in The Ice Age. |
| The End | Finish a run in The Future. |
| The Infinite | Finish a run in The Jurassic and The End. |
